Article
Premature ovarian failure (POF) syndrome: towards the molecular clinical analysis of its genetic complexity.
Current medicinal chemistry - 1 Jan 2006
Fassnacht W, Mempel A, Strowitzki T, Vogt P H
Abstract excerpt
The Premature Ovarian Failure (POF) syndrome is a very heterogeneous clinical disorder due probably to the complex genetic networks controlling human folliculogenesis. Clinical subgroups of POF patients whose aetiology of ovarian failure is based on the same genetic factors are therefore difficult to establish. Some experimental evidence suggests that these genes might be clustered on the female sex chromosome in...
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