Article
Effect of genetic factors on opioid action.
Current opinion in anaesthesiology - 1 Aug 2009
Kosarac Branka, Fox Amanda A, Collard Charles D
Abstract excerpt
PURPOSE OF REVIEW: Opioid administration is a mainstay of anesthetic practice both for treating acute perioperative pain and for chronic pain syndromes. Growing pharmacogenetic data make it evident that many opiate-related phenomena are influenced by genetics. Genetic variation may significantly affect opiate absorption, distribution, metabolism, excretion and toxicity. We provide a current review of opiate...
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