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Article

Role of pharmacogenetics in variable response to drugs: focus on opioids

21 Dec 2007

Abstract excerpt

Pharmacogenetics is the study of the role of genetics in inter-individual variability to drug response and therapy. This review provides a comprehensive report of the present status of pharmacogenetic studies for opioid drugs. Opioid analgesics are widely used clinically for pain management, and inter-patient variability with opioid therapy is often reported. Information on genetic polymorphisms in enzymes,...

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PMID: 18370860
DOI: 10.1517/17425255.4.1.77

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