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Article

Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development.

PloS one - 25 May 2009

Kulangara Caroline, Kajava Andrey V, Corradin Giampietro, Felger Ingrid

Abstract excerpt

BACKGROUND: The availability of the P. falciparum genome has led to novel ways to identify potential vaccine candidates. A new approach for antigen discovery based on the bioinformatic selection of heptad repeat motifs corresponding to alpha-helical coiled coil structures yielded promising results. To elucidate the question about the relationship between the coiled coil motifs and their sequence conservation, we...

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Identifiers

PMID: 19492090
DOI: 10.1371/journal.pone.0005419
PMCID: PMC2683929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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