Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of κB Kinase β Expression

2 Jun 2009

Abstract excerpt

N-myc downstream regulated gene 1 (NDRG1)/Cap43 expression is a predictive marker of good prognosis in patients with pancreatic cancer as we reported previously. In this study, NDRG1/Cap43 decreased the expression of various chemoattractants, including CXC chemokines for inflammatory cells, and the recruitment of macrophages and neutrophils with suppression of both angiogenesis and growth in mouse xenograft...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to FOXO transcription factor regulation
Share to Mechanisms of cancer metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19491262
DOI: 10.1158/0008-5472.can-08-4882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

N-myc Downstream Regulated Gene 1/Cap43 Suppresses Tumor Growth and Angiogenesis of Pancreatic Cancer through Attenuation of Inhibitor of κB Kinase β ExpressionPMID 19491262Read ↗

Tumor Growth Suppression in Pancreatic Cancer by a Putative Metastasis Suppressor Gene <i>Cap43/NDRG1/Drg-1</i> through Modulation of AngiogenesisSemantic proximity Read ↗

The CCDC43-ADRM1 axis regulated by YY1, promotes proliferation and metastasis of gastric cancerSemantic proximity Read ↗

Caffeic acid phenethyl ester upregulates N-myc downstream regulated gene 1 via ERK pathway to inhibit human oral cancer cell growth in vitro and in vivoSemantic proximity Read ↗

Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis.Semantic proximity Read ↗

Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta.Semantic proximity Read ↗

Function of nuclear factor kappaB in pancreatic cancer metastasis.Semantic proximity Read ↗

Identification of Therapeutic Targets and Prognostic Biomarkers Among CC Chemokines in the Pancreatic Adenocarcinoma MicroenvironmentSemantic proximity Read ↗

Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 RegulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.