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Article

Tumor Growth Suppression in Pancreatic Cancer by a Putative Metastasis Suppressor Gene <i>Cap43/NDRG1/Drg-1</i> through Modulation of Angiogenesis

15 Jun 2006

Abstract excerpt

Cap43 has been identified as a nickel- and calcium-induced gene, and is also known as N-myc downstream-regulated gene 1 (NDRG1), Drg-1 and rit42. It is also reported that overexpression of Cap43 suppresses metastasis of some malignancies, but its precise role remains unclear. In this study, we asked how Cap43 could modulate the tumor growth of pancreatic cancer. Stable Cap43 cDNA transfectants of pancreatic...

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PMID: 16778198
DOI: 10.1158/0008-5472.can-06-0183

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