Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of mitochondrial allele 4216C with increased risk for sepsis-related organ dysfunction and shock after burn injury.

Shock (Augusta, Ga.) - 1 Jan 2010

Huebinger Ryan M, Gomez Ruben, McGee Daphne, Chang Ling-Yu, Bender Jessica E, O'Keeffe Terence, Burris Agnes M, Friese Susan M, Purdue Gary F, Hunt John L, Arnoldo Brett D, Horton Jureta W, Barber Robert C

Abstract excerpt

Impaired mitochondrial activity has been linked to increased risk for clinical complications after injury. Furthermore, variant mitochondrial alleles have been identified and are thought to result in decreased mitochondrial activity. These include a nonsynonymous mitochondrial polymorphism (T4216...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Young Adult
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Multiple Organ Failure

Share to NADH Dehydrogenase

Share to Polymerase Chain Reaction

Share to Sepsis

Source

Identifiers

PMID: 19487983
DOI: 10.1097/SHK.0b013e3181a99508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19487983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of mitochondrial allele 4216C with increased risk for sepsis-related organ dysfunction and shock after burn injury.PMID 19487983Read ↗

Association of mitochondrial allele 4216C with increased risk for complicated sepsis and death after traumatic injury.Semantic proximity Read ↗

Specific polymorphic variation in the mitochondrial genome and increased in-hospital mortality after severe trauma.Semantic proximity Read ↗

CD14-159 C allele is associated with increased risk of mortality after burn injury.Semantic proximity Read ↗

Tumor necrosis factor gene variation and the risk of mortality after burn injury: a cohort study.Semantic proximity Read ↗

The role of mitochondrial DNA mutations in a Han Chinese population on sepsis pathogenesis.Semantic proximity Read ↗

TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury.Semantic proximity Read ↗

Innate immunity SNPs are associated with risk for severe sepsis after burn injury.Semantic proximity Read ↗

Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b <sup>+</sup> Leukocytes from Patients with SepsisSemantic proximity Read ↗

Searching for alleles associated with complicated outcomes after burn injury.Semantic proximity Read ↗

IL-10 polymorphism associated with decreased risk for mortality after burn injury.Semantic proximity Read ↗

Mitochondrial DNA Haplogroups and Delirium During SepsisSemantic proximity Read ↗

Detecting genetic predisposition for complicated clinical outcomes after burn injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.