Article
Altered phenotype and function of NK cells infiltrating human papillomavirus (HPV)-associated genital warts during HIV infection.
Clinical immunology (Orlando, Fla.) - 1 Feb 2014
Bere Alfred, Tayib Shahila, Kriek Jean-Mari, Masson Lindi, Jaumdally Shameem Z, Barnabas Shaun L, Carr William H, Allan Bruce, Williamson Anna-Lise, Denny Lynette, Passmore Jo-Ann S
Abstract excerpt
HIV-infected individuals experience more persistent HPV infections and are less likely to resolve genital warts. This study compared phenotype and functions of NK and T cells from genital warts and blood from 67 women. We compared in vitro functional responses of NK and T cells by multiparametric flow cytometry. HIV+ women had significantly lower frequencies of CD4 T cells in warts (p = 0.001) and blood (p =...
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