Article
Inflammatory human leucocyte antigen genotypes are not a risk factor in chronic subdural hematoma development.
Acta neurochirurgica - 1 Sept 2023
Jensen Thorbjørn Søren Rønn, Fugleholm Kåre, Ekstrøm Claus Thorn, Bruunsgaard Helle
Abstract excerpt
BACKGROUND: Chronic subdural hematoma (CSDH) pathophysiology has undergone a paradigm shift from being regarded as solely traumatic to be driven mainly by inflammation. Human leucocyte antigen (HLA) is a gene complex involved in antigen processing and presentation to T lymphocytes, thereby mediating the adaptive immune responses. As specific HLA profiles are associated with inflammatory diseases, patients with a...
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