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Article

Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia

28 Dec 2000

Abstract excerpt

BACKGROUND: Fluorescence in situ hybridization has improved the detection of genomic aberrations in chronic lymphocytic leukemia. We used this method to identify chromosomal abnormalities in patients with chronic lymphocytic leukemia and assessed their prognostic implications. METHODS: Mononuclear cells from the blood of 325 patients with chronic lymphocytic leukemia were analyzed by fluorescence in situ...

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PMID: 11136261
DOI: 10.1056/nejm200012283432602

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