Article
Anchorage-independent cell growth signature identifies tumors with metastatic potential.
Oncogene - 6 Aug 2009
Mori S, Chang J T, Andrechek E R, Matsumura N, Baba T, Yao G, Kim J W, Gatza M, Murphy S, Nevins J R
Abstract excerpt
The oncogenic phenotype is complex, resulting from the accumulation of multiple somatic mutations that lead to the deregulation of growth regulatory and cell fate controlling activities and pathways. The ability to dissect this complexity, so as to reveal discrete aspects of the biology underlying the oncogenic phenotype, is critical to understanding the various mechanisms of disease as well as to reveal...
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