Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways.

International journal of molecular sciences - 17 Sept 2021

Sevilla Lisa M, Jiménez-Panizo Alba, Alegre-Martí Andrea, Estébanez-Perpiñá Eva, Caelles Carme, Pérez Paloma

Abstract excerpt

Endogenous glucocorticoids (GCs) are steroid hormones that signal in virtually all cell types to modulate tissue homeostasis throughout life. Also, synthetic GC derivatives (pharmacological GCs) constitute the first-line treatment in many chronic inflammatory conditions with unquestionable therapeutic benefits despite the associated adverse effects. GC actions are principally mediated through the GC receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Glucocorticoids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia

Share to MAP Kinase Signaling System

Share to Metabolism, Inborn Errors

Share to Receptors, Glucocorticoid

Share to Respiration Disorders

Share to Skin Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 34576214
DOI: 10.3390/ijms221810049
PMCID: PMC8465023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways.PMID 34576214Read ↗

Glucocorticoid receptors: finding the middle groundSemantic proximity Read ↗

Current concepts in glucocorticoid resistance.Semantic proximity Read ↗

The Glucocorticoid Receptor: Isoforms, Functions, and Contribution to Glucocorticoid SensitivitySemantic proximity Read ↗

Primary generalized glucocorticoid resistance and hypersensitivity.Semantic proximity Read ↗

Glucocorticoid resistance in inflammatory diseases.Semantic proximity Read ↗

Primary Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes: A 2021 UpdateSemantic proximity Read ↗

The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious DiseasesSemantic proximity Read ↗

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid ReceptorSemantic proximity Read ↗

A General Introduction to Glucocorticoid BiologySemantic proximity Read ↗

Acquired Glucocorticoid Resistance Due to Homologous Glucocorticoid Receptor Downregulation: A Modern Look at an Age-Old ProblemSemantic proximity Read ↗

Mechanisms and resistance in glucocorticoid control of inflammationSemantic proximity Read ↗

Minireview: Latest Perspectives on Antiinflammatory Actions of GlucocorticoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.