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Article

The influence of heart valve leaflet matrix characteristics on the interaction between human mesenchymal stem cells and decellularized scaffolds.

Biomaterials - 1 Sept 2009

Iop Laura, Renier Vera, Naso Filippo, Piccoli Martina, Bonetti Antonella, Gandaglia Alessandro, Pozzobon Michela, Paolin Adolfo, Ortolani Fulvia, Marchini Maurizio, Spina Michele, De Coppi Paolo, Sartore Saverio, Gerosa Gino

Abstract excerpt

The potential for in vitro colonization of decellularized valves by human bone marrow mesenchymal stem cells (hBM-MSCs) towards the anisotropic layers ventricularis and fibrosa and in homo- vs. heterotypic cell-ECM interactions has never been investigated. hBM-MSCs were expanded and characterized by immunofluorescence and FACS analysis. Porcine and human pulmonary valve leaflets (p- and hPVLs, respectively)...

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Identifiers

PMID: 19481252
DOI: 10.1016/j.biomaterials.2009.04.031

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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