Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model.

doi:10.1016/j.biomaterials.2013.04.059

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Article

Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model.

Biomaterials - 1 Oct 2013

Weber Benedikt, Dijkman Petra E, Scherman Jacques, Sanders Bart, Emmert Maximilian Y, Grünenfelder Jürg, Verbeek Renier, Bracher Mona, Black Melanie, Franz Thomas, Kortsmit Jeroen, Modregger Peter, Peter Silvia, Stampanoni Marco, Robert Jérôme, Kehl Debora, van Doeselaar Marina, Schweiger Martin, Brokopp Chad E, Wälchli Thomas, Falk Volkmar, Zilla Peter, Driessen-Mol Anita, Baaijens Frank P T, Hoerstrup Simon P

Abstract excerpt

Heart valve tissue engineering based on decellularized xenogenic or allogenic starter matrices has shown promising first clinical results. However, the availability of healthy homologous donor valves is limited and xenogenic materials are associated with infectious and immunologic risks. To address such limitations, biodegradable synthetic materials have been successfully used for the creation of living...

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PMID: 23810254
DOI: 10.1016/j.biomaterials.2013.04.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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