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Article

Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.

Brain research bulletin - 30 Jun 2009

Brooks Simon, Fielding Steven, Döbrössy Màtè, von Hörsten Stephan, Dunnett Stephen

Abstract excerpt

In accordance with the genetic nature of Huntington's disease (HD), transgenic and knock-in mouse models have been developed that have sought to recapitulate the key features of the human condition. To date, only a single rat model has been developed, the tgHD rat that carries 51 CAG repeats. The tgHD rat has many of the anatomical and behavioural characteristics of HD, including cognitive, emotional and motor...

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Identifiers

PMID: 19480990
DOI: 10.1016/j.brainresbull.2009.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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