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Article

Somatic mitochondrial mutations in pilocytic astrocytoma.

Cancer genetics and cytogenetics - 1 Jul 2009

Lueth Maria, Wronski Lena, Giese Almut, Kirschner-Schwabe Renate, Pietsch Torsten, von Deimling Andreas, Henze Guenter, Kurtz Andreas, Driever Pablo Hernáiz

Abstract excerpt

The most common brain tumors in childhood and adolescence are low grade pilocytic astrocytomas (PA). Given that an increasing number of mitochondrial defects have been related to brain tumors and cancer in general, we asked whether PAs harbor mutations of mitochondrial DNA (mtDNA). Sequencing analysis of the complete mitochondrial genome of tumor tissue and corresponding blood samples from 19 patients with PA was...

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Identifiers

PMID: 19480934
DOI: 10.1016/j.cancergencyto.2009.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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