Article
Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling.
Diabetologia - 1 Aug 2009
Song X Y, Lee S Y, Ma R C W, So W Y, Cai J H, Tam C, Lam V, Ying W, Ng M C Y, Chan J C N
Abstract excerpt
AIMS/HYPOTHESIS: Cardiovascular and renal diseases share common risk factors. We used structural equation modelling (SEM) to evaluate the independent and combined effects of phenotypes and genotypes implicated in cardiovascular diseases on renal function in type 2 diabetes. METHODS: 1,188 type 2 diabetic patients were stratified into high-risk and low-risk groups according to bimodal distributions of the...
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