Article
Regulation of superoxide dismutase genes: implications in disease.
Free radical biology & medicine - 15 Aug 2009
Miao Lu, St Clair Daret K
Abstract excerpt
Numerous short-lived and highly reactive oxygen species (ROS) such as superoxide (O2(.-)), hydroxyl radical, and hydrogen peroxide are continuously generated in vivo. Depending upon concentration, location, and intracellular conditions, ROS can cause toxicity or act as signaling molecules. The cellular levels of ROS are controlled by antioxidant enzymes and small-molecule antioxidants. As major antioxidant...
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