Article
Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients.
Antiviral therapy - 1 Jan 2009
Soria Alessandro, Porten Klaudia, Fampou-Toundji Jean-Calvin, Galli Laura, Mougnutou Rose, Buard Vincent, Kfutwah Anfumbom, Vessière Aurelia, Rousset Dominique, Teck Roger, Calmy Alexandra, Ciaffi Laura, Lazzarin Adriano, Gianotti Nicola
Abstract excerpt
BACKGROUND: The lack of HIV type-1 (HIV-1) viral load (VL) monitoring in resource-limited settings might favour the accumulation of resistance mutations and thus hamper second-line treatment efficacy. We investigated the factors associated with resistance after the initiation of antiretroviral therapy (ART) in the absence of virological monitoring. METHODS: Cross-sectional VL sampling of HIV-1-infected patients...
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