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Article

Evolutionary selection between alternative modes of gene regulation.

Proceedings of the National Academy of Sciences of the United States of America - 2 Jun 2009

Gerland Ulrich, Hwa Terence

Abstract excerpt

Microorganisms employ a wealth of gene regulatory mechanisms to adjust their growth programs to variations in the environment. It was pointed out long ago [Savageau M (1977) Proc Natl Acad Sci USA 74: 5647-5651] that the particular mode of gene regulation employed may be correlated with the "demand" on the regulated gene, i.e., how frequently the gene product is needed in its natural habitat. An evolutionary...

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Identifiers

PMID: 19470486
DOI: 10.1073/pnas.0808500106
PMCID: PMC2690017

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