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Article

Disentangling the effects of selection and loss bias on gene dynamics.

Proceedings of the National Academy of Sciences of the United States of America - 11 Jul 2017

Iranzo Jaime, Cuesta José A, Manrubia Susanna, Katsnelson Mikhail I, Koonin Eugene V

Abstract excerpt

We combine mathematical modeling of genome evolution with comparative analysis of prokaryotic genomes to estimate the relative contributions of selection and intrinsic loss bias to the evolution of different functional classes of genes and mobile genetic elements (MGE). An exact solution for the...

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Identifiers

PMID: 28652353
DOI: 10.1073/pnas.1704925114
PMCID: PMC5514749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-28652353-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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