Article
FYN kinase gene: another glutamatergic gene associated with bipolar disorder?
Neuropsychobiology - 1 Jan 2009
Szczepankiewicz Aleksandra, Rybakowski Janusz K, Skibinska Maria, Dmitrzak-Weglarz Monika, Leszczynska-Rodziewicz Anna, Wilkosc Monika, Hauser Joanna
Abstract excerpt
Several genes of the glutamatergic system have been implicated in both schizophrenia and bipolar disorder. The Src family tyrosine kinase FYN plays a key role in the interaction between brain-derived neurotrophic factor and glutamatergic receptor N-methyl-D-aspartate. Although no association between FYN gene polymorphisms and schizophrenia has been demonstrated, in our previous paper we found an association...
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