Article
Polymorphisms of the Fyn kinase gene and a performance on the Wisconsin Card Sorting Test in schizophrenia.
Psychiatric genetics - 1 Jun 2007
Rybakowski Janusz K, Borkowska Alina, Skibinska Maria, Hauser Joanna
Abstract excerpt
The glutamatergic system has been implicated in the pathogenesis and prefrontal cortex dysfunctions in schizophrenia. The Src-family tyrosine kinase Fyn plays a key role in the interaction between brain-derived neurotrophic factor and glutamatergic receptor N-methyl-D-aspartate, in prefrontal cor...
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