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Article

Flux balance impact degree: a new definition of impact degree to properly treat reversible reactions in metabolic networks.

Bioinformatics (Oxford, England) - 1 Sept 2013

Zhao Yang, Tamura Takeyuki, Akutsu Tatsuya, Vert Jean-Philippe

Abstract excerpt

MOTIVATION: Metabolic pathways are complex systems of chemical reactions taking place in every living cell to degrade substrates and synthesize molecules needed for life. Modeling the robustness of these networks with respect to the dysfunction of one or several reactions is important to understand the basic principles of biological network organization, and to identify new drug targets. While several approaches...

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PMID: 23828783
DOI: 10.1093/bioinformatics/btt364
PMCID: PMC3740629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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