Article
No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort.
Neurobiology of aging - 1 Mar 2011
Fernández-Santiago Rubén, Sharma Manu, Berg Daniela, Illig Thomas, Anneser Johanna, Meyer Thomas, Ludolph Albert, Gasser Thomas
Abstract excerpt
A recent genome-wide association study (GWAS) found significant association of six single nucleotide polymorphisms (SNPs) in the gene FLJ10986 with sporadic amyotrophic lateral sclerosis (SALS). Another independent GWAS reported significant association of one SNP in the gene inositol 1,4,5-triphosphate receptor 2 (ITPR2) with SALS. These studies provided conflicting results. We examined the six most significant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.