Article
Lack of association of LINGO1 rs9652490 and rs11856808 SNPs with familial essential tremor.
European journal of neurology - 1 Aug 2011
Lorenzo-Betancor O, García-Martín E, Cervantes S, Agúndez J A G, Jiménez-Jiménez F J, Alonso-Navarro H, Luengo A, Coria F, Lorenzo E, Irigoyen J, Pastor P
Abstract excerpt
BACKGROUND: Essential tremor (ET) is a frequent movement disorder with a substantial family aggregation. A genome-wide association study has recently shown that LINGO1 gene variants are associated with increased risk of ET. METHODS: We intended to replicate these findings by genotyping rs9652490 and rs11856808 in a series of 226 familial ET subjects and 1117 healthy controls from referral movement disorder...
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