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Article

Muscle contraction is necessary to maintain joint progenitor cell fate.

Developmental cell - 1 May 2009

Kahn Joy, Shwartz Yulia, Blitz Einat, Krief Sharon, Sharir Amnon, Breitel Dario A, Rattenbach Revital, Relaix Frederic, Maire Pascal, Rountree Ryan B, Kingsley David M, Zelzer Elazar

Abstract excerpt

During embryogenesis, organ development is dependent upon maintaining appropriate progenitor cell commitment. Synovial joints develop from a pool of progenitor cells that differentiate into various cell types constituting the mature joint. The involvement of the musculature in joint formation has long been recognized. However, the mechanism by which the musculature regulates joint formation has remained elusive....

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Identifiers

PMID: 19460349
DOI: 10.1016/j.devcel.2009.04.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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