Article
Major genetic effects in glaucoma: commingling analysis of optic disc parameters in an older Australian population.
Investigative ophthalmology & visual science - 1 Nov 2009
van Koolwijk Leonieke M E, Healey Paul R, Hitchings Roger A, Mitchell Paul, Sham Pak C, McGuffin Peter, Viswanathan Ananth C
Abstract excerpt
PURPOSE: To test the hypothesis that there is a major genetic determinant of vertical disc diameter (VDD) and vertical cup-to-disc ratio (VCDR) in a large, population-based sample. METHODS: Data were collected from 3654 individuals, 49 years of age or older, participating in the Blue Mountains Eye Study. VDD and VCDR were determined from stereo optic disc photographs. Commingling analyses in SKUDRIVER/SKUMIX were...
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