Article
Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants.
Journal of experimental botany - 1 Jan 2009
Abe Kiyomi, Osakabe Keishi, Ishikawa Yuichi, Tagiri Akemi, Yamanouchi Hiroaki, Takyuu Toshio, Yoshioka Terutaka, Ito Takuya, Kobayashi Masatomo, Shinozaki Kazuo, Ichikawa Hiroaki, Toki Seiichi
Abstract excerpt
BRCA2 is a breast tumour susceptibility factor with functions in maintaining genome stability through ensuring efficient double-strand DNA break (DSB) repair via homologous recombination. Although best known in vertebrates, fungi, and higher plants also possess BRCA2-like genes. To investigate the role of Arabidopsis BRCA2 genes in DNA repair in somatic cells, transposon insertion mutants of the AtBRCA2a and...
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