Article
BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.
The New phytologist - 1 Jan 2012
Seeliger Katharina, Dukowic-Schulze Stefanie, Wurz-Wildersinn Rebecca, Pacher Michael, Puchta Holger
Abstract excerpt
• Mutations in the breast cancer susceptibility gene 2 (BRCA2) are correlated with hereditary breast cancer in humans. Studies have revealed that mammalian BRCA2 plays crucial roles in DNA repair. Therefore, we wished to define the role of the BRCA2 homologs in Arabidopsis in detail. • As Arabidopsis contains two functional BRCA2 homologs, an Atbrca2 double mutant was generated and analyzed with respect to...
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