Article
Simple and sensitive method for identification of human DNA by allele-specific polymerase chain reaction of FOXP2.
Journal of forensic sciences - 1 Jul 2009
Hiroshige Kenichi, Soejima Mikiko, Nishioka Tomoki, Kamimura Shigeo, Koda Yoshiro
Abstract excerpt
The forkhead box P2 (FOXP2) gene is specifically involved in speech and language development in humans. The sequence is well conserved among many vertebrate species but has accumulated amino acid changes in the human lineage. The aim of this study was to develop a simple method to discriminate between human and nonhuman vertebrate DNA in forensic specimens by amplification of a human-specific genomic region. In...
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