Article
No Evidence for Recent Selection at FOXP2 among Diverse Human Populations.
Cell - 6 Sept 2018
Atkinson Elizabeth Grace, Audesse Amanda Jane, Palacios Julia Adela, Bobo Dean Michael, Webb Ashley Elizabeth, Ramachandran Sohini, Henn Brenna Mariah
Abstract excerpt
FOXP2, initially identified for its role in human speech, contains two nonsynonymous substitutions derived in the human lineage. Evidence for a recent selective sweep in Homo sapiens, however, is at odds with the presence of these substitutions in archaic hominins. Here, we comprehensively reanalyze FOXP2 in hundreds of globally distributed genomes to test for recent selection. We do not find evidence of recent...
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