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Article

Production of a novel influenza vaccine using insect cells: protection against drifted strains

1 Jan 2007

Abstract excerpt

A recombinant trivalent hemagglutinin (HA) vaccine produced in cell culture using the baculovirus expression system provides an attractive alternative to the current egg-based influenza vaccine (Trivalent Inactivated Influenza Vaccine [TIV]) manufacturing process. The HA genes from the annual World Health Organization-recommended strains are cloned, expressed, and purified using a general purification process....

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PMID: 19453478
DOI: 10.1111/j.1750-2659.2006.00007.x

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