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A Rationally Designed H5 Hemagglutinin Subunit Vaccine Provides Broad-Spectrum Protection against Various H5Nx highly Pathogenic Avian Influenza Viruses in Chickens

2024-07-12

Abstract excerpt

The evolution of the H5 highly pathogenic avian influenza (HPAI) viruses has led to the emergence of distinct groups with genetically similar clusters of hemagglutinin (HA) sequences. In this study, a consensus H5 HA sequence was cloned into the baculovirus expression system. The HA protein was expressed in baculovirus-infected insect cells and utilized as the antigen for the production of an oil emulsion-based H5...

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Literature Corpus work: 1a97b984-43bf-56c2-8313-2486bf01a9b5
DOI: 10.20944/preprints202407.1019.v1

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A Rationally Designed H5 Hemagglutinin Subunit Vaccine Provides Broad-Spectrum Protection against Various H5Nx highly Pathogenic Avian Influenza Viruses in ChickensDOI 10.20944/preprints202407.1019.v1Read

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