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Article

Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin-dependent protein kinase II.

Journal of neurochemistry - 1 Jul 2009

Raveendran Rajeevkumar, Devi Suma Priya Sudarsana, Mayadevi Madhavan, Steephan Mathew, Santhoshkumar Thankayyan R, Cheriyan John, Sanalkumar Rajendran, Pradeep Kurup K, James Jackson, Omkumar Ramakrishnapillai V

Abstract excerpt

Ca(2+) influx through NMDA-type glutamate receptor at excitatory synapses causes activation of post-synaptic Ca(2+)/calmodulin-dependent protein kinase type II (CaMKII) and its translocation to the NR2B subunit of NMDA receptor. The major binding site for CaMKII on NR2B undergoes phosphorylation at Ser1303, in vivo. Even though some regulatory effects of this phosphorylation are known, the mode of...

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PMID: 19453375
DOI: 10.1111/j.1471-4159.2009.06108.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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