Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP.

Nucleic acids research - 1 Jul 2009

Ameur Adam, Rada-Iglesias Alvaro, Komorowski Jan, Wadelius Claes

Abstract excerpt

UNLABELLED: Disease-associated SNPs detected in large-scale association studies are frequently located in non-coding genomic regions, suggesting that they may be involved in transcriptional regulation. Here we describe a new strategy for detecting regulatory SNPs (rSNPs), by combining computational and experimental approaches. Whole genome ChIP-chip data for USF1 was analyzed using a novel motif finding algorithm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatin Immunoprecipitation

Share to Oligonucleotide Array Sequence Analysis

Share to Regulatory Elements, Transcriptional

Share to Transcription Factors

Share to Transcription, Genetic

Share to Upstream Stimulatory Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19451166
DOI: 10.1093/nar/gkp381
PMCID: PMC2709586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP.PMID 19451166Read ↗

Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.Semantic proximity Read ↗

Identification of functional cis-regulatory polymorphisms in the human genome.Semantic proximity Read ↗

HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease.Semantic proximity Read ↗

A novel method for in silico identification of regulatory SNPs in human genome.Semantic proximity Read ↗

atSNP: transcription factor binding affinity testing for regulatory SNP detection.Semantic proximity Read ↗

Integrating regulatory features data for prediction of functional disease-associated SNPs.Semantic proximity Read ↗

Regulatory SNPs in complex diseases: their identification and functional validation.Semantic proximity Read ↗

MotifMap: a human genome-wide map of candidate regulatory motif sites.Semantic proximity Read ↗

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants.Semantic proximity Read ↗

Large-scale computational identification of regulatory SNPs with rSNP-MAPPER.Semantic proximity Read ↗

On the identification of potential regulatory variants within genome wide association candidate SNP sets.Semantic proximity Read ↗

Novel approach to functional SNPs discovery from genome-wide data reveals promising variants for colon cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.