HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease.

Abstract excerpt

More than 90% of common variants associated with complex traits do not affect proteins directly, but instead the circuits that control gene expression. This has increased the urgency of understanding the regulatory genome as a key component for translating genetic results into mechanistic insights and ultimately therapeutics. To address this challenge, we developed HaploReg (http://compbio.mit.edu/HaploReg) to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Attention Deficit Disorder with Hyperactivity
• Share to Data Mining