Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DAT1 gene polymorphism in alcoholism: a family-based association study.

Biological psychiatry - 1 Mar 1999

Franke P, Schwab S G, Knapp M, Gänsicke M, Delmo C, Zill P, Trixler M, Lichtermann D, Hallmayer J, Wildenauer D B, Maier W

Abstract excerpt

BACKGROUND: The present study tests the hypothesis that the 9-repeat allele of the dopamine transporter gene (DAT1; SLC6A3) is more frequent in alcohol-dependent probands--and in particular those with severe withdrawal symptoms (seizures and/or delirium)--compared to nonalcoholics. METHODS: To avoid stratification effects, the family-based association approach of Falk and Rubinstein was used in our sample of 87...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Severity of Illness Index
Share to Substance Withdrawal Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Seizures

Share to Alcoholism

Share to Dopamine Plasma Membrane Transport Proteins

Share to Membrane Glycoproteins

Share to Membrane Transport Proteins

Share to Nerve Tissue Proteins

Source

Identifiers

PMID: 10088054
DOI: 10.1016/s0006-3223(98)00135-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DAT1 gene polymorphism in alcoholism: a family-based association study.PMID 10088054Read ↗

Polymorphisms in the dopamine transporter gene (SLC6A3/DAT1) and alcohol dependence in humans: a systematic review.Semantic proximity Read ↗

Modification of alcohol withdrawal by the A9 allele of the dopamine transporter gene.Semantic proximity Read ↗

Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium.Semantic proximity Read ↗

Association of the dopamine transporter gene with alcoholism.Semantic proximity Read ↗

The A9 allele of the dopamine transporter gene is associated with delirium tremens and alcohol-withdrawal seizure.Semantic proximity Read ↗

The 3' part of the dopamine transporter gene DAT1/SLC6A3 is associated with withdrawal seizures in patients with alcohol dependence.Semantic proximity Read ↗

Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population.Semantic proximity Read ↗

[Combination of DAT and DBH gene polymorphisms with a family history of alcohol use disorders increases the risk of withdrawal seizures and delirium tremens during alcohol withdrawal in alcohol-dependent men].Semantic proximity Read ↗

[Case-control, family based and screening for DNA sequence variation in the dopamine transporter gene polymorphism DAT 1 in alcohol dependence].Semantic proximity Read ↗

Meta-Analysis Reveals Significant Association of the 3'-UTR VNTR in SLC6A3 with Alcohol Dependence.Semantic proximity Read ↗

The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis.Semantic proximity Read ↗

The A9 allele of the dopamine transporter gene increases the risk of visual hallucinations during alcohol withdrawal in alcohol-dependent women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.