Article
The A9 allele of the dopamine transporter gene is associated with delirium tremens and alcohol-withdrawal seizure.
Biological psychiatry - 1 Jan 2003
Gorwood Philip, Limosin Frédéric, Batel Philippe, Hamon Michel, Adès Jean, Boni Claudette
Abstract excerpt
BACKGROUND: The dopamine transporter (DAT) plays a key role in homeostatic regulation of dopaminergic neurotransmission and could thus be involved in the variability of two severe alcohol-withdrawal symptoms, alcohol-withdrawal seizure (AWS) and delirium tremens (DT). Interestingly, an association was found between the DAT gene (9-copy repeat) and the risk for these symptoms in two previous case-control studies....
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