Article
Proangiogenic Contribution of Adiponectin toward Mammary Tumor Growth <i>In vivo</i>
15 May 2009
Abstract excerpt
PURPOSE: Adipocytes represent one of the most abundant constituents of the mammary gland. They are essential for mammary tumor growth and survival. Metabolically, one of the more important fat-derived factors ("adipokines") is adiponectin (APN). Serum concentrations of APN negatively correlate with body mass index and insulin resistance. To explore the association of APN with breast cancer and tumor angiogenesis,...
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