Tumor Metabolic Reprogramming by Adipokines as a Critical Driver of Obesity-Associated Cancer Progression.

doi:10.3390/ijms22031444

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Article

Tumor Metabolic Reprogramming by Adipokines as a Critical Driver of Obesity-Associated Cancer Progression.

International journal of molecular sciences - 1 Feb 2021

Pham Duc-Vinh, Park Pil-Hoon

Abstract excerpt

Adiposity is associated with an increased risk of various types of carcinoma. One of the plausible mechanisms underlying the tumor-promoting role of obesity is an aberrant secretion of adipokines, a group of hormones secreted from adipose tissue, which have exhibited both oncogenic and tumor-suppressing properties in an adipokine type- and context-dependent manner. Increasing evidence has indicated that these...

Topics

Adipokines
Adipose Tissue
Adiposity
Animals
Disease Progression
Glucose
Glycolysis
Humans
Inflammation
Leptin
Lipid Metabolism
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitochondria

Neoplasms

Nicotinamide Phosphoribosyltransferase

Obesity

Oxidation-Reduction

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 33535537
DOI: 10.3390/ijms22031444
PMCID: PMC7867092

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