Article
Functional promoter -94 ins/del ATTG polymorphism in NFKB1 gene is associated with bladder cancer risk in a Chinese population.
PloS one - 1 Jan 2013
Li Pengchao, Gu Jinbao, Yang Xiao, Cai Hongzhou, Tao Jun, Yang Xuejian, Lu Qiang, Wang Zengjun, Yin Changjun, Gu Min
Abstract excerpt
BACKGROUND: A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of cancer. This study aims to determine whether the polymorphism is associated with risk of bladder cancer. MATERIALS AND METHODS: TaqMan assay was used to determine genotype among 609 cases and 640 controls in a Chinese...
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