Article
Recipient genotype is a predictor of allograft cytokine expression and outcomes after pediatric cardiac transplantation.
Journal of the American College of Cardiology - 19 May 2009
Auerbach Scott R, Manlhiot Cedric, Reddy Sushma, Kinnear Caroline, Richmond Marc E, Gruber Dorota, McCrindle Brian W, Deng Liyong, Chen Jonathan M, Addonizio Linda J, Chung Wendy K, Mital Seema
Abstract excerpt
OBJECTIVES: This study sought to investigate the influence of recipient renin-angiotensin-aldosterone system (RAAS) genotype on cardiac function, rejection, and outcomes after heart transplantation. BACKGROUND: The RAAS influences cardiac function and up-regulates inflammatory/immune pathways. Little is known about the effect of recipient RAAS polymorphisms in pediatric cardiac transplantation. METHODS: Patients...
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