Article
Gene polymorphisms impact the risk of rejection with hemodynamic compromise: a multicenter study.
Transplantation - 27 Jun 2011
Girnita Diana M, Ohmann Erin L, Brooks Maria M, Webber Steven A, Burckart Gilbert J, Ferrell Robert E, Ranganathan Sarangarajan, Chinnock Richard, Canter Charles, Addonizio Linda, Bernstein Daniel, Kirklin James K, Naftel David C, Zeevi Adriana
Abstract excerpt
BACKGROUND: Rejection with hemodynamic compromise (RHC) is associated with high mortality in heart recipients. This study investigates the association between genetic polymorphisms and RHC in pediatric heart recipients. METHODS: Data from 532 pediatric heart recipients from six centers in the Pediatric Heart Transplant Study were analyzed for time to RHC by recipient race, age at transplantation, and genotype at...
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