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Article

Sequence conservation provides the best prediction of the role of proline residues in p13suc1.

Journal of molecular biology - 4 Aug 2000

Schymkowitz J W, Rousseau F, Itzhaki L S

Abstract excerpt

The unique nature of the proline side-chain imposes severe constraints on the polypeptide backbone, and thus it seems likely that it plays a special structural or functional role in the architecture of proteins. We have investigated the role of proline residues in suc1, a member of the cyclin-dependent kinase (cks) family of proteins, whose known function is to bind to and regulate the activity of the major...

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Identifiers

PMID: 10926502
DOI: 10.1006/jmbi.2000.3958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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