Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae.

doi:10.1093/genetics/145.3.615

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Article

Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae.

Genetics - 1 Mar 1997

Baker S H, Frederick D L, Bloecher A, Tatchell K

Abstract excerpt

Protein phosphatase type 1, encoded by GLC7 in Saccharomyces cerevisiae, is an essential serine/threonine phosphatase implicated in the regulation of a diverse array of physiological functions. We constructed and examined 20 mutant alleles of GLC7 in which codons encoding clusters of charged resi...

Topics

Alanine
Alleles
Fungal Proteins
Genes, Lethal
Glucose
Glycogen
Mutagenesis
Phosphoprotein Phosphatases
Saccharomyces cerevisiae
Spores, Fungal

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