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Article

Nuclear protein import is reduced in cells expressing nuclear envelopathy-causing lamin A mutants.

Experimental cell research - 15 Aug 2009

Busch Albert, Kiel Tilman, Heupel Wolfgang-M, Wehnert Manfred, Hübner Stefan

Abstract excerpt

Lamins, which form the nuclear lamina, not only constitute an important determinant of nuclear architecture, but additionally play essential roles in many nuclear functions. Mutations in A-type lamins cause a wide range of human genetic disorders (laminopathies). The importance of lamin A (LaA) in the spatial arrangement of nuclear pore complexes (NPCs) prompted us to study the role of LaA mutants in nuclear...

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Identifiers

PMID: 19442658
DOI: 10.1016/j.yexcr.2009.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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