Article
Hemopoiesis in Ph-negative chronic myeloproliferative disorders.
Current stem cell research & therapy - 1 May 2009
Spanoudakis Emmanouil, Tsatalas Costas
Abstract excerpt
Chronic myeloproliferative disorders (cMPDs) are clonal hemopoietic malignancies arising at the multipotent stem cell level. These conditions are characterized by increased blood count, marrow hyperplasia and extramedulary hemopoiesis. Vascular events might complicate their course, and transformation to either acute leukemia or myelofibrosis can finally occur. Among cMPDs, Polycythemia Vera (PV), Essential...
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