Article
Evaluation of C1q genomic region in minority racial groups of lupus.
Genes and immunity - 1 Jul 2009
Namjou B, Gray-McGuire C, Sestak A L, Gilkeson G S, Jacob C O, Merrill J T, James J A, Wakeland E K, Li Q-Z, Langefeld C D, Divers J, Ziegler J, Moser K L, Kelly J A, Kaufman K M, Harley J B
Abstract excerpt
Complement cascade plasma proteins play a complex role in the etiopathogenesis of systemic lupus erythematosus (SLE). Hereditary C1q deficiency has been strongly related to SLE; however, there are very few published SLE studies that evaluate the polymorphisms of genes encoding for C1q (A, B and C...
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