Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rec8 guides canonical Spo11 distribution along yeast meiotic chromosomes.

Molecular biology of the cell - 1 Jul 2009

Kugou Kazuto, Fukuda Tomoyuki, Yamada Shintaro, Ito Masaru, Sasanuma Hiroyuki, Mori Saori, Katou Yuki, Itoh Takehiko, Matsumoto Kouji, Shibata Takehiko, Shirahige Katsuhiko, Ohta Kunihiro

Abstract excerpt

Spo11-mediated DNA double-strand breaks (DSBs) that initiate meiotic recombination are temporally and spatially controlled. The meiotic cohesin Rec8 has been implicated in regulating DSB formation, but little is known about the features of their interplay. To elucidate this point, we investigated the genome-wide localization of Spo11 in budding yeast during early meiosis by chromatin immunoprecipitation using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Chromosomes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Breaks, Double-Stranded

Share to DNA Topoisomerases, Type II

Share to Endodeoxyribonucleases

Share to Exodeoxyribonucleases

Share to Hydroxyurea

Share to S Phase

Source

Open in PubMed Open full text

Identifiers

PMID: 19439448
DOI: 10.1091/mbc.e08-12-1223
PMCID: PMC2704158

Genes

REC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rec8 guides canonical Spo11 distribution along yeast meiotic chromosomes.PMID 19439448Read ↗

Sites of strong Rec12/Spo11 binding in the fission yeast genome are associated with meiotic recombination and with centromeres.Semantic proximity Read ↗

Locally, meiotic double-strand breaks targeted by Gal4BD-Spo11 occur at discrete sites with a sequence preference.Semantic proximity Read ↗

Meiotic cohesins modulate chromosome compaction during meiotic prophase in fission yeast.Semantic proximity Read ↗

Interacting Genomic Landscapes of REC8-Cohesin, Chromatin, and Meiotic Recombination in Arabidopsis.Semantic proximity Read ↗

The kleisin subunit controls the function of meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1Semantic proximity Read ↗

Cohesins are required for meiotic DNA breakage and recombination in Schizosaccharomyces pombe.Semantic proximity Read ↗

Numerical and spatial patterning of yeast meiotic DNA breaks by Tel1.Semantic proximity Read ↗

Coupling meiotic chromosome axis integrity to recombination.Semantic proximity Read ↗

Cohesin regulates homology search during recombinational DNA repair.Semantic proximity Read ↗

Methods to Map Meiotic Recombination Proteins in Saccharomyces cerevisiae.Semantic proximity Read ↗

Meiotic cohesin paralogs govern cell survival by exhibiting flexibility in partner choiceSemantic proximity Read ↗

Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.